FIG. 4.

Transmission electron micrographs of C. neoformans strain 3501 cells interacting with D. discoideum. (A) C. neoformans is being engulfed by the pseudopods of a D. discoideum cell 2 h postinfection. (B) Two individual phagocytic events by one D. discoideum cell 2 h postinfection. In one event the C. neoformans cells are in membrane-bound vacuoles. The second event shows a budding C. neoformans cell in a vacuole. (Magnifications: ×24,000 [A] and ×18,000 [B]). The micrographs shown are representative of what was observed under the microscope.