TABLE 2.
Numbers of IFN-γ-producing cells 10 weeks after the onset of vaccination (10 weeks after the initial DNA vaccination and 4 weeks after BCG vaccination)
| Group | Log10 no. of IFN-γ spot-forming cells/106 PBMCa
|
|||
|---|---|---|---|---|
| Avian PPD | Bovine PPD | Hsp 65 | Hsp 70 | |
| Nonvaccinated | 1.98 ± 0.15 | 1.62 ± 0.21 | 1.65 ± 0.15 | 1.47 ± 0.19 |
| DNA | 2.15 ± 0.16 | 2.06 ± 0.12b | 1.76 ± 0.17 | 1.94 ± 0.16 |
| DNA/BCG | 2.05 ± 0.13 | 1.97 ± 0.14 | 1.32 ± 0.19 | 1.36 ± 0.21 |
| BCG | 1.91 ± 0.15 | 1.69 ± 0.12 | 1.27 ± 0.08 | 1.25 ± 0.09 |
a
Log10 number of IFN-γ spot-forming cells per 106 peripheral blood mononuclear cells (PBMC). The values are means ± standard errors of the means.
b
The value is significantly different from the value for the nonvaccinated group (P < 0.05).