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. 2003 Sep;71(9):5306–5313. doi: 10.1128/IAI.71.9.5306-5313.2003

TABLE 2.

Comparison of the virulence of strains of the B. cepacia complex in a chronic respiratory infection model

Strain Virulence (CFU/ml/lung)a
% Pathology on day 7 p.i.a
Day 7 p.i. Day 21 p.i.
B. cepacia genomovar I
    Cep509 8.1 × 105 ± 6.4 × 105 1.2 × 105 ± 1.4 × 105b 43.0 ± 2.0
B. multivorans
    C5393 1.3 × 106 ± 1.4 × 106 3.7 × 105 ± 1.5 × 105 13.3 ± 5.9
    C1576 1.2 × 105 ± 1.7 × 105 4.5 × 104 ± 4.6 × 104 9.0 ± 4.6
B. cepacia genomovar III
    K56-2 1.5 × 106 ± 2.4 × 106e ND 40.5 ± 4.2e
    PC715j 3.5 × 105 ± 3.4 × 105f ND 22.8 ± 10.8f
    J2315 4.6 × 103 ± 7.8 × 103 5.0 × 102c 38.0 ± 21.0
    Cep511 2.7 × 105 ± 2.2 × 105 3.3 × 103 ± 5.1 × 103 12.7 ± 1.53
    J415 3.1 × 105 ± 5.2 × 105 6.5 × 103 ± 1.2 × 104 13.0 ± 1.73
B. stabilis
    LMG 14086 3.3 × 102 ± 2.9 × 102 0 20.0 ± 1.7
    LMG 14294 0 0 16.0 ± 5.6
B. vietnamiensis
    PC259 1.2 × 104 ± 2.0 × 104 2.0 × 102 ± 1.7 × 102 19.7 ± 0.6
    FC441 8.5 × 102 ± 6.6 × 102 7.1 × 103 ± 9.3 × 103d 29.0 ± 1.0
a

Values are means ± standard deviations for three animals unless noted otherwise. ND, not determine

b

Values are mean ± standard deviation for four animals.

c

Values are for one animal (one animal died on day 1 p.i., and one animal died on day 2 p.i.).

d

Values are mean ± standard deviation for five animals.

e

Data previously reported by Sokol et al. (32).

f

Values are means ± standard deviations for eight animals in the experiment previously described by Sokol et al. (32).