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Sections of ears from mice receiving live vaccine with or without CpG ODN. Ears were harvested at 4 weeks postvaccination and were processed for hematoxylin and eosin staining. Ear sections were prepared from healthy C57BL/6 mice (A and D) or from mice vaccinated with 104 metacyclic promastigotes alone (C and F) or with 50 μg of CpG ODN (B and E). Magnification, ×10 (A, B, and C) and ×100 (D, E, and F). Bar, 10 μm.
