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Secondary parameters: tmax, Cmax, AUC(0,24 h) and Cmax/AUC(0,24 h) for the respective regimens A–D (median, 25% quartile, 75% quartile; (*P < 0.05, regimens A vs C, A vs D, B vs C, B vs D) regimens A: acidic urine pH, low urinary flow; B: acidic urine pH, high urinary flow; C: alkaline urine pH, low urinary flow; D: alkaline urine pH, high urinary flow.
