TABLE 3.
Hexon secondary structure
| X-ray models
|
Homology modelsb
|
|||||
|---|---|---|---|---|---|---|
| Ad5 residues | Ad2 residues | Region | Elementa | C68 residues | Ad4 residues | CELO residues |
| NT | 2-5 (310) | 2-5 (310) | ||||
| 5-12 | 5-12 | NT | α0 | 6-11 | 6-11 | 12-18 |
| 18-23 | 18-23 | NT | α1 | 19-24 | 19-24 | |
| 24-35 | 24-35 | NT | α2 | 25-36 | 25-36 | 30-39 |
| 40-44 | 40-44 | NT | 310 | 40-45 | 40-45 | 46-50 |
| 64-67 | 64-67 | V1 | B1 | 65-68 | 65-68 | 70-73 |
| 71-74 | 71-74 | V1 | B1 | 72-75 | 72-75 | 77-80 |
| 78-87 | 78-87 | V1 | C1 | 79-88 | 79-88 | 85-92 |
| 93-94, 98-107 | 93-94, 98-107 | V1 | D1 | 93-108 | 93-108 | 99-100, 104-113 |
| 132-134 | 132-134 | DE1 | β1 | 134-135 | 138-139 | |
| 166-168 | 173-175 | DE1 | β2 | 140-141 | ||
| 173-174 | DE1 | β3 | 147-148 | 142-144 | ||
| 178-179 | 185-186 | DE1 | β4 | 151-152 | 152-156 | |
| 182-188 | 189-190 | DE1 | β5 | 158-163 | 162-166 | 162-166 |
| 191-194 | DE1 | β5a | 166-169 | 169-172 | ||
| 218-223 | 229-234 | DE1 | β6 | 193-194 | 193-195 | 197-198, 201-202 |
| DE1 | 204-206 (310) | |||||
| 236-237 | 247-248 | DE1 | β6a | |||
| 262-266 | 273-277 | DE1 | β7 | 232-234 | 233-238 | |
| 283-288 | 295-300 | DE1 | β8 | 259-263 | 248-253 | |
| 292-293 | 304-305 | DE1 | β9 | |||
| 297-301 | 309-313 | DE1 | β10 | 262-264 | ||
| 310-316 | 323-328 | DE1 | 310 | 293-297 | 294-299 | 275-280 |
| 317-320 | 329-332 | DE1 | β11 | 283-285 | ||
| 326-328 | 338-340 | V1 | E1 | 309-311 | 310-312 | 291-293 |
| 330-333 | 342-345 | V1 | 310(1) | |||
| 340-344 | 352-356 | V1 | 310(2) | |||
| 346-349 | 358-361 | V1 | E1 | 331-332 | 332-333 | 311-314 |
| V1 | 316-317 (310) | |||||
| Nonregular | Nonregular | V1 | F1 | Nonregular | Nonregular | Nonregular |
| 364-377 | 376-389 | V1 | α1 | 347-360 | 348-361 | 329-340 |
| 384-387 | 396-399 | V1 | 310(3) | |||
| 394-399 | 406-411 | FG1 | α1 | 359-364 | ||
| 400-401 | 412-413 | FG1 | β1 | 382-385 | 385-386 | 365-366 |
| 412-413 | 423-425 | FG1 | β2 | 395-396 | 397-397 | 377-378 |
| 423-425 | 435-437 | FG1 | β3 | 404-408 | 404-409 | |
| 428-429 | 440-441 | FG1 | β4 | 411-413 | ||
| 439-440 | 456-457 | FG1 | β4a | 421-423 | ||
| 449-451 | 465-467 | FG1 | β5 | 431-435 | 434-441 | |
| 459-460 | 475-477 | FG1 | β6 | 441-442 | 444-445 | 427-428 |
| 462-476 | 478-492 | FG1 | α2 | 444-462 | 447-465 | 430-444 |
| 477-480 | 493-496 | FG1 | 310(1) | |||
| 481-485 | 497-501 | FG1 | 310(2) | 463-467 | 466-470 | |
| 499-506 | 515-522 | FG1 | α3 | 484-489 | ||
| 509-514 | 525-530 | FG1 | 310(3) | 491-496 | 494-499 | |
| 522-523 | 538-539 | FG1 | β7 | 503-506 | 506-507 | 493-494 |
| 525-530 | 541-546 | FG1 | α3a | 507-513 | 510-516 | 496-501 (310) |
| 539-550 | 555-566 | FG1 | α4 | 523-530 | 526-533 | 510-519 |
| 554-561 | 570-577 | V1 | G1 | 536-541 | 539-544 | 525-527, 530-532 |
| V1 | 549-552 (310) | 552-555 (310) | 538-541 (310) | |||
| 572-573 | 588-589 | V1 | G1 | 554-555 | 557-558 | 543-544 |
| 576-585 | 592-601 | V1 | H1 | 558-567 | 561-570 | 548-552, 554-555 |
| 587-591 | 603-607 | V1 | α2 | 569-573 | 572-576 | 558-562 |
| 592-594 | 608-610 | V1 | H1 | 574-576 | 577-579 | 563-565 |
| V1 | 581-586 (α) | 584-589 (α) | ||||
| 606-617 | 622-633 | V1 | I1 | 588-601 | 591-604 | 577-588 |
| 622-634 | 638-650 | VC | α1 | 604-615 | 607-618 | 593-604 |
| 635-639 | 651-655 | VC | 310 | |||
| 640-643 | 656-659 | VC | β1 | 622-624 | 625-627 | 611-613 |
| 648-655 | 664-671 | V2 | B2 | 630-636 | 633-640 | 619-625 |
| 661-669 | 677-685 | V2 | C2 | 644-651 | 647-654 | 632-640 |
| 676-683 | 692-699 | V2 | D2 | 658-665 | 661-668 | 647-654 |
| 685-687 | 701-703 | DE2 | 310 | 667-669 | 670-672 | 656-658 |
| 704-709 | 720-725 | DE2 | α1 | 675-680 | ||
| 713-715 | 729-731 | V2 | 310(1) | |||
| 717-724 | 733-740 | V2 | E2 | 699-706 | 702-709 | 688-695 |
| 728-730 | 744-746 | V2 | F2 | 710-712 | 713-715 | 699-701 |
| 742-743 | 758-759 | V2 | F2 | 724-725 | 727-728 | 713-714 |
| 750-753 | 763-769 | V2 | 310(2) | 730-734 | 723-725 | |
| V2 | 736-737 (β) | 739-740 (β) | 727-728 (β) | |||
| V2 | 742-743 (β) | 745-746 (β) | 733-734 (β) | |||
| 761-774 | 777-790 | V2 | α1 | 744-756 | 747-759 | 735-746 |
| 784-788 | FG1 | 310 | ||||
| 792-796 | 808-813 | FG2 | α1 | 774-778 | 777-781 | |
| 797-805 | 814-821 | FG2 | β1 | 779-787 | 782-790 | 770-772, 775-778 |
| FG2 | 785-786 (β) | |||||
| FG2 | 791-792 (β) | |||||
| 817-821 | 833-837 | FG2 | 310 | 799-803 | 802-806 | |
| FG2 | 810-811 (β) | 813-814 (β) | ||||
| FG2 | 818-819 (β) | 821-822 (β) | ||||
| 857-865 | 873-880 | FG2 | β2 | 838-846 | 842-850 | 849-852, 855-857 |
| 870-873 | 886-889 | V2 | G2 | 851-854 | 855-858 | 862-865 |
| 886-889 | 902-906 | V2 | 310(3) | 866-870 | 870-874 | 877-881 |
| 890-895 | 906-910 | V2 | α3 | 871-887 | 875-881 | 882-888 |
| 898-906 | 914-922 | V2 | H2 | 879-887 | 883-891 | 890-898 |
| 913-920 | 929-936 | V2 | I2 | 894-901 | 898-905 | 905-912 |
| 922-928 | 938-944 | VC | β2 | 906-909 | 910-912 | 914-923 |
| 936-942 | 952-958 | VC | β3 | 917-919 | 926-934 | |
| VC | 928-929 (β) | 937-941 (310) | ||||
a
New secondary structure observed in the X-ray models is underlined.
b
Predicted secondary structure is shown in parentheses.