Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PD modelling of diuresis using the effect-compartment model. Emax is the maximum diuretic response attributed to the drug, EC50 is the frusemide excretion rate producing 50% of Emax, s represents the sigmoidicity factor, ke0 is the first-order rate constant for drug loss from the effect site and E0 is the estimated basal diuresis.
