FIG. 6.
PRV challenge infection of mice after intravenous transfer of recombinant ORFV-immune sera. Sera were obtained from BALB/c mice after twofold immunization with each ORFV recombinant alone and passively transferred to naïve recipients. The survival times of individual animals are depicted after transfer of the indicated volumes of D1701-VrVgC immune sera (A) or D1701-VrVgD immune sera (B). Mice receiving serum from twofold D1701-VrV-immunized animals served as a control. Challenge infection with 300 LD50s of PRV was performed 24 h after serum transfer.