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ORFV recombinant-mediated protection of immune-deficient mice
| Mouse strain | No. of survivors/total (%)
|
||
|---|---|---|---|
| D1701-VrVgCa | D1701-VrVgDa | Begonia%b | |
| μMT | 7/8 (87.5) | 7/8 (87.5) | 4/5 (80.0) |
| CD4−/− | 8/8 (100) | 4/8 (50.0) | 2/4 (50.0) |
| CD8−/− | 8/8 (100) | 6/6 (100) | 3/3 (100) |
| PKOB | 8/8 (100) | 8/8 (100) | 5/5 (100) |
Two immunizations.
Single vaccination.
