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. 2007 Mar 26;403(Pt 2):243–250. doi: 10.1042/BJ20061123

Figure 2. Effect of CG7 on the IR in CHO/IR cells.

Figure 2

(A) Cells were incubated with CG7 at the indicated concentrations with (closed bars) or without 1 nM insulin (open bars) for 15 min at 37 °C, and direct effects of CG7 on IRβ auto-phosphorylation were measured by ELISA. Values are means±S.D. for three experiments. ***, P<0.001 indicates values significantly greater than with CG7 alone. (B) Cells were incubated in the presence of the indicated concentrations of insulin (black-dotted bars) or insulin plus 1 μg/ml CG7 (white-dotted bars) for 15 min at 37 °C, and IR β-subunit auto-phosphorylation was measured by ELISA. Values are means±S.D. for three experiments. **, P<0.005 indicates values significantly greater than insulin alone.