Table 2.
Effect of sildenafil on secondary semen analysis parameters. For ejaculate viscosity, data are presented as adjusted geometric means.
| Parameter | Normal values | Sildenafil | Placebo* | Sildenafil–placebo (95% confidence intervals) |
|---|---|---|---|---|
| Sperm count (×106) | 100–500 | 389.7 | 367.4 | 22.3 (−44.7, 88.7) |
| Sperm density (×106 ml−1) | 50–150 | 117.9 | 107.4 | 10.5 (−8.5, 29.4) |
| Abnormal forms (%) | <85 | 82.03 | 80.88 | 1.16 (−0.01, 2.32) |
| Living sperm (%) | >80 | 83.22 | 84.94 | −1.7 (−5.3, 1.8) |
| Ejaculate volume (ml) | 2.5–6 | 3.663 | 3.636 | 0.027 (−0.299, 0.352) |
| Ejaculate viscosity (s) | <10 | 3.803 | 4.285 | 88.7% (72.4, 108.8)† |
*
P = Not significant for all comparisons vs sildenafil
†
ratio between geometric means.