Table 4.

Interaction between covariates in the final population pharmacokinetic model and the prevalence of covariate combinations.

	0–20		20–40		40–60		60–80		80–100
AST (IU l−1) CYP3A4 (yes/no)	no	yes	no	yes	no	yes	no	yes	no	yes
Age (y)	Number of Patients
10–30	2	0	13	0	0	0	0	0	0	0
30–50	64	3	148	19	13	3	2	0	0	1
50–60	210	50	532	89	25	5	2	1	0	1
70–90	29	9	80	31	1	2	1	0	0	0