. 2002 Feb;53(2):111–122. doi: 10.1046/j.0306-5251.2001.01548.x

Table 1.

Frequency of CYP2D6^*1 or^*2 alleles (causing ‘normal’ enzyme activity) and some alleles causing no or deficient CYP2D6 activity in three different ethnic populations.

CYP2D6 alleles	Functional mutation	Consequence	Swedish	Allele frequency (%) Chinese	Zimbabwean
^1 or ^2			69	43	54
^*3	A2637 del	Frame shift	2	0	0
^*4	G1934A	Splicing defect	22	0–1	2
^*5	Gene deletion	No enzyme	4	6	4
^*10	C188T	Unstable enzyme	n.d.	51	6
^*17	C1111T	Reduced affinity	n.d.	n.d.	34

n.d. = not determined.

Data are from original publications [23, 25, 27] and reviews [4, 5].