Table 3.
90% Confidence intervals for the ratio of the mean AUC and Css values.
| Norelgestromin | Ethinyloestradiol | ||||
|---|---|---|---|---|---|
| Test/Reference | Parameter | 90% CI† | Ratio (%)* | 90% CI† | Ratio (%)* |
| Arm/Abdomen | Css | 130.5 | 120.0, 142.0 | 124.6 | 114.0, 136.2 |
| AUC(0, 240 h) | 130.2 | 119.6, 141.7 | 125.4 | 115.0, 136.7 | |
| Buttock/Abdomen | Css | 125.0 | 114.9, 135.9 | 117.3 | 107.3, 128.2 |
| AUC(0, 240 h) | 125.8 | 115.5, 136.9 | 119.9 | 110.0, 130.7 | |
| Torso/Abdomen | Css | 125.4 | 115.3, 136.3 | 124.4 | 113.8, 136.0 |
| AUC(0, 240 h) | 124.6 | 114.5, 135.7 | 124.4 | 114.1, 135.7 | |
| Arm/Buttock | Css | 104.5 | 96.1, 113.6 | 106.3 | 97.2, 116.2 |
| AUC(0, 240 h) | 103.5 | 95.1, 112.7 | 104.6 | 95.9, 114.0 | |
| Torso/Buttock | Css | 100.3 | 92.2, 109.1 | 106.1 | 97.1, 116.0 |
| AUC(0, 240 h) | 99.1 | 91.0, 107.9 | 103.8 | 95.2, 113.2 | |
| Torso/Arm | Css | 96.0 | 88.3, 104.4 | 99.9 | 91.3, 109.2 |
| AUC(0, 240 h) | 95.7 | 88.0, 104.2 | 99.2 | 91.0, 108.2 | |
CI=confidence interval.
*
Ratio of geometric mean for test/reference.
†
90% CI for ratio of geometric mean for test/reference.