Figure 2.
β-Chemokine production inversely correlates with resistance of PBMCs to HIV-1JR-CSF infection. MIP-1α, MIP-1β, and RANTES production in vitro by PBMCs was inversely correlated with the ability of the same cells to support replication of HIV-1JR-CSF as determined by p24 levels (dark bars) at day 7 after viral challenge. There was an inverse correlation between β-chemokine and p24 levels [Spearman's correlation test for MIP-1α (P = 0.009), for MIP-1β (P = 0.03), and for RANTES (P = 0.04)].