. 2002 Mar;53(3):312–317. doi: 10.1046/j.0306-5251.2001.01568.x

Table 2.

Pharmacokinetic parameters for paracetamol.

	Control	Charcoal at 1 h	Lavage and charcoal at 1 h	Charcoal at 2 h
t_max (h)	1.7 (0.4–2.3)	1.3 (0.7–3.1)	0.9 (0.5–1.6)	1.5 (0.7–2.3)
C_max (mg l⁻¹)	41.8 (30.1–90.5)	12.38 (7.2–58.7)^*	27.4 (4.1–62.2)^*	40.3 (11.8–56.1)
AUC(0,∞) (mg l⁻¹ h)	189.8 (119.1–235.4)	52.9 (19.7–135.8)^*	88.1 (19.2–170.4)^*	151.7 (53.8–116.2)^*
t_½ (h)	2.2 (1.1–3.3)	1.7 (1.1–2.4)	1.7 (1.3–2.0)	1.8 (0.9–2.1)

Data are given as median (range) for all 12 subjects.

Significantly different (minimum P < 0.05) from controls. ‘Control’ indicates day of ingestion of paracetamol without subsequent intervention.