Table 4.
Average cardiovascular parameters during the last 3 weeks of each treatment.†
Placebo | Diltiazem | Nifedipine | P value | |
---|---|---|---|---|
Blood pressure(mmHg) | ||||
systolic | 113±1 | 116±2 | 114±1 | NS |
diastolic | 70±1 | 70±1 | 67±1 | |
Heart rate(beats min−1) | 75±2 | 72±2 | 83±2 | 0.0001 |
P-R interval | 0.165±0.003 | 0.178±0.003 | 0.160±0.002 | 0.0001 |
Cardiovascular parameters were within normal limits for all subjects during the screening visit, a requirement for entrance into the study.