Table 3.
Analyses of secondary parameters (intention to treat population).
| Mean (median*) response | |||||
|---|---|---|---|---|---|
| Parameter | SR paracetamol (n = 203) | IR paracetamol (n = 200) | Treatment difference SR paracetamol – IR paracetamol | 95% CI | P value |
| Pain during day† | 1.50 | 1.46 | 0.04 | (−0.072, 0.151) | P = 0.490 |
| Pain on waking† | 1.13 | 1.12 | 0.02 | (−0.105, 0.139) | P = 0.785 |
| Pain on walking† | 1.56 | 1.50 | 0.06 | (−0.066, 0.177) | P = 0.369 |
| Pain at rest† | 1.09 | 1.07 | 0.02 | (−0.097, 0.138) | P = 0.736 |
| Pain relief§ | 1.75 | 1.71 | 0.03 | (−0.141, 0.208) | P = 0.705 |
| Number of times woken during night* | 0.14 | 0.14 | 0.00 | (0.000, 0.000) | P = 0.630 |
| Number of patients woken at least once | 114 (56.7%) | 103 (52.0%) | |||
| Minutes of morning stiffness* | 0.00 | 0.00 | 0.00 | (0.000, 0.000) | P = 0.943 |
| Number of patients with morning stiffness | 96 (47.8%) | 93 (47.7%) | |||
| Number of rescue medication tablets taken* | 0.00 | 0.00 | 0.00 | (0.000, 0.000) | P = 0.955 |
| Number of patients taking rescue medication | 47 (23.2%) | 47 (23.5%) | |||
*
Median.
†
A score of 1–2 denotes that the level of pain was between ‘mild’ to ‘moderate’.
§
A score of 1–2 denotes that the level of pain relief was between ‘a little’ and ‘some’.