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Patients covariates identified in the screening step and in the final population pharmacokinetic model for intravenous vinorelbine.
| Parameter | Screening of covariates | Final population model |
|---|---|---|
| CLtot | Plt, BSA, Wt/Crs, creatinine clearance, γGT, age, gender, ALP, SGOT, SGPT | BSA*, Wt/Crs, Plt |
| V | Plt, BSA, Gender | Plt, Gender |
BSA was only kept into the final model developed from the entire data set.
