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. 2002 May;53(5):485–491. doi: 10.1046/j.1365-2125.2002.01587.x

Table 2.

Pharmacokinetic parameters of R- and S-warfarin.

	R-warfarin		S-warfarin
	+entacapone	+placebo	+entacapone	+placebo
C_max (µg ml⁻¹)	0.51±0.17	0.47±0.15	0.64±0.23	0.62±0.21
t_max (h)	1.0 (0.5–3.0)	1.0 (0.5–2.0)	1.0 (0.5–3.0)	1.0 (0.5–2.0)
C_min (µg ml⁻¹)	0.24±0.09	0.21±0.09	0.36±0.15	0.36±0.14
C_av (µg ml⁻¹)	0.35±0.12	0.30±0.11	0.47±0.18	0.45±0.16
AUC_ss (µg ml⁻¹ h)	8.4±2.8	7.2±2.6	11.4±4.4	10.8±3.9
PTF (%)	78±19	90±29	60±15	60±16

Data are presented as mean±s.d. (n = 12) for all variables, with the exception of t_max which is expressed as median (range).