Table 4.
Parameter | Treatment | Geometric mean | Range | n |
---|---|---|---|---|
Cmax (ng ml−1) | A-I | 105.8 | 44.0–162 | 7 |
B-I | 66.2 | 33.0–132 | 6 | |
C-I | 77.7 | 61.0–131 | 9 | |
AUC(96,120 h) (ng ml−1 h) | A-I | 1956 | 682–3339 | 7 |
B-I | 1181 | 700–1923 | 6 | |
C-I | 1443 | 1236–2146 | 9 | |
t1/2 (h) | A-I | 22.4 | 12.5–38.5 | 4 |
B-I | 26.1 | 15.5–51.6 | 4 | |
C-I | 34.6 | 16.8–91.2 | 9 |