Table 2.
Regulatory utility of classification of drugs by a ‘therapeutic class'.
| Drug | Original therapeutic class | Clinically developed for use as |
|---|---|---|
| Imipramine | Antihistamine and sedative | Antidepressant |
| Chlorpromazine | Sedative | Neuroleptic |
| Terodiline | Antianginal | Urinary incontinence |
| Terfenadine | Neuroleptic | H1-antihistamine |
| Melperone | Neuroleptic | α-blocker |
| Sotalol | β-blocker | Class III antiarrhythmic |
| Nifenalol | β-blocker | Class III antiarrhythmic |
| Sildenafil | Antianginal | Erectile dysfunction |
| Amiodarone | Antianginal | Antiarrhythmic |
| Butyrophenones | Analgesic | Neuroleptic |
| Iproniazid | Anti-tuberculous | Antidepressant (MAOI) |
| Ethmozine | Neuroleptic | Class I antiarrhythmic |