Table 3.

Likely prognostic significance of 1x clinical dose mean maximum or peak placebo-corrected effects on QTc interval.

Mean maximum or peak placebo-corrected increase in QTc interval	Likely potential torsadogenic risk
≤5 ms	None
6–10 ms	Unlikely
11–15 ms	Possible
16–20 ms	Probable
21–25 ms	Almost definite
≥26 ms	Definite