H.p.l.c. chromatograms of (a) drug-free human plasma, (b) drug free human plasma spiked with cis-OH-perhexiline, hexadiline and perhexiline, and (c) plasma from a patient administered perhexiline. Retention times were 2.9 min for cis-OH-perhexiline, 8.1 and 8.6 min for the two peaks formed by hexadiline, and 9.9 min for perhexiline.