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Profile of mood states activity scores (all values are median; range).
| Time (h) | Amitriptyline | St John's wort | Placebo |
|---|---|---|---|
| 0 | 28.0 (19.0–36.0) | 30.5 (15.0–39.0) | 31.0 (24.0–37.0) |
| 0.5 | 24.5 (10.0–34.0)* | 31.0 (15.0–37.0) | 30.0 (21.0–35.0) |
| 3 | 22.5 (13.0–37.0)* | 30.5 (15.0–36.0) | 29.5 (20.0–35.0) |
| 5 | 25.5 (12.0–35.0)* | 28.5 (17.0–34.0) | 28.5 (19.0–34.0) |
P < 0.05 when compared post hoc with pretreatment (time 0) and with placebo.
