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Adverse events.
| Adverse event | Amitriptyline | St John's wort extract | Placebo |
|---|---|---|---|
| Dry mouth | 9 | – | 2 |
| Sedation | 12 | 1 | – |
| Dizziness | 7 | – | 1 |
| Emotional irritability | 4 | – | – |
| Lack of concentration | 4 | 1 | – |
| Nausea | – | – | 1 |
| Headaches | – | 1 | – |
| Elevation of serum transaminases | 1 | – | – |
| Excessive appetite | 1 | – | – |
