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The odds ratios (ORs) and their 95% confidence intervals (95%CIs) of serious upper gastrointestinal bleeding in patients using one or more nonsteroidal anti-inflammatory drugs.
| Number of NSAIDs taken | Cases | Controls | OR (*) | 95% CI |
|---|---|---|---|---|
| 1 | 1159 | 1075 | 4.9 | (4.4, 5.6) |
| 2 | 112 | 50 | 10.7 | (7.3, 15.7) |
| 3 or more | 9 | 1 | 60.0 | (6.9, 525.9) |
All odds ratios are relative to nonuse of any NANSAID or aspirin and are adjusted for use of anticoagulants, smoking, and history of UGI problems.
