Table 3.
Risk of first-time acute myocardial infarction in current NSAID users, stratified by individual agents.
| NSAID use | Cases (n = 3315) | Controls (n = 13139) | Adjusted*odds ratio(95% CI) |
|---|---|---|---|
| Non-users | 1502 | 6236 | 1.0 (Referent) |
| Individual NSAIDs† | |||
| Ibuprofen | 60 | 204 | 1.17 (0.87–1.58) |
| Diclofenac | 97 | 277 | 1.38 (1.08–1.77) |
| Piroxicam | 10 | 28 | 1.65 (0.78–3.49) |
| Fenbufen | 7 | 13 | 2.06 (0.80–5.30) |
| Ketoprofen | 15 | 48 | 1.39 (0.77–2.51) |
| Indomethacin | 15 | 56 | 1.03 (0.58–1.85) |
| Flurbiprofen | 8 | 14 | 2.26 (0.93–5.46) |
| Naproxen | 19 | 105 | 0.68 (0.42–1.13) |
adjusted for smoking status, body mass index, hormone replacement therapy and aspirin
only NSAIDs presented with ≥5 exposed cases