Table 3.
The mean log urinary caffeine metabolic ratio (AFMU + 1 U + 1X)/1,7 U (MRc), s.d. and 95% confidence interval (CI) in different CYP1A2 genotype groups divided according to smoking status (n = number of subjects).
| Genotype | Smoking status | Mean log MR c ± s.d. | 95% CI | n |
|---|---|---|---|---|
| *1 A/*1 A | Non-smokers | 0.71 ± 0.31 | (0.63, 0.79) | 58 |
| Smokers | 0.73 ± 0.31 | (0.59, 0.87) | 18 | |
| *1 A/*1F | Non-smokers | 0.75 ± 0.33 | (0.71, 0.79) | 307 |
| Smokers | 0.86 ± 0.34 | (0.78, 0.94) | 67 | |
| *1F/*1F | Non-smokers | 0.76 ± 0.32 | (0.73, 0.79) | 375 |
| Smokers | 0.79 ± 0.29 | (0.73, 0.85) | 79 |