Table 1.

The study design.

Study	Dosing condition	Step	Dose (mg)	Number of subjects
Single dose (Preliminary)	In fasting state	1	3	2
		1b	3	2
		2	10	2
		3	30	2
		4	100	2
Single dose (Main)	In fasting state	5	150	8*
		6	200	8*
	Post-prandial	7	150	8*
Multiple dose	Post-prandial	8	150	8*

^*Including 2 placebo-treated subjects.