Table 1.
Summary of serum lipid and lipoprotein concentrations after morning and evening administration of rosuvastatin.
| Parameter | Morning n = 21 Mean baseline (mmol l−1) | Mean % change | Evening n = 21 Mean baseline(mmol l−1) | Mean % change | Treatment effecta (90% CI) |
|---|---|---|---|---|---|
| LDL-C | 3.12 | −41.3 | 3.09 | −44.2 | 2.9 (−0.09, 5.85) |
| Total cholesterol | 4.94 | −30.9 | 4.90 | −31.8 | 0.8 (−1.21, 2.89) |
| Triglycerides | 1.19 | −17.1 | 1.27 | −22.7 | 5.7 (−0.39, 11.70) |
| HDL-C | 1.28 | −9.6 | 1.23 | −4.9 | −4.7 (−7.80, 1.54) |
| Apolipoprotein A-I | 16.6 | −6.0 | 20.3 | −3.4 | −2.6 (−5.40, 0.18) |
| Apolipoprotein B | 22.8 | −32.4 | 24.8 | −35.3 | 2.9 (0.25, 5.57) |
HDL-C – high-density lipoprotein cholesterol. LDL-C – low-density lipoprotein cholesterol.
a
Treatment effect = difference of morning-evening least square means.