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Predictive performance for the different sampling strategies of E7070 AUC for the 1 h infusion.
| Strategy | Number of samples | % Bias (95% CI) | % Precision (95% CI) |
|---|---|---|---|
| 1 | 2 | 8.4 (−12, 29) | 43 (28, 54) |
| 2 | 3 | 4.8 (−11, 21) | 33 (24, 41) |
| 3 | 3 | 4.9 (−5.1, 15) | 22 (16, 26) |
| 4 | 3 | 6.7 (−4.9, 19) | 26 (8.9, 35) |
| 5 | 4 | 3.8 (−5.9, 14) | 21 (15, 25) |
| 6 | 4 | 1.2 (−6.9, 9.3) | 17 (0, 24) |
| 7 | 4 | 0.74 (−5.6, 7.1) | 13 (5.6, 18) |
| 8 | 5 | −0.67 (−5.6, 4.3) | 10 (7.1, 13) |
CI = confidence interval.
