Table 4.
Univariate outcomes based on the Rodey classification
| Outcome | Matched, % (range) | Minor mismatch, % (range) | Major mismatch, % (range) | P* |
|---|---|---|---|---|
| Overall survival | ||||
| 1 y | 51 (48-53) | 37 (29-45) | 37 (32-43) | < .001 |
| 2 y | 43 (41-45) | 28 (21-35) | 31 (26-37) | < .001 |
| 5 y | 36 (34-38) | 21 (15-27) | 26 (21-32) | < .001 |
| Disease-free survival | ||||
| 1 y | 46 (43-48) | 29 (22-37) | 33 (27-39) | < .001 |
| 2 y | 39 (37-41) | 25 (18-32) | 27 (22-33) | < .001 |
| Death in remission | ||||
| 1 y | 37 (35-39) | 52 (44-61) | 53 (47-59) | < .001 |
| 2 y | 41 (39-43) | 56 (48-64) | 56 (50-62) | < .001 |
| Relapse | ||||
| 1 y | 17 (16-19) | 19 (13-26) | 14 (10-18) | .344 |
| 2 y | 20 (18-21) | 19 (13-27) | 16 (12-21) | .385 |
| Grade 2-4 acute GvHD | ||||
| 100 d | 50 (48-52) | 62 (55-59) | 54 (47-62) | .002 |
| Grade 3-4 acute GvHD | ||||
| 100 d | 30 (28-32) | 46 (39-52) | 41 (33-48) | < .001 |
| Chronic GvHD | ||||
| 2 y | 45 (43-47) | 39 (32-46) | 40 (32-48) | .124 |
| Engraftment | ||||
| 28 dn | 90 (88-91) | 85 (79-90) | 82 (76-88) | .027 |
*
P values are the pointwise P values comparing 3 groups.