Table 1.

Morphological analysis by μCT of femurs from μMT/μMT B-cell KO mice and WT controls

Morphological parameters	WT mice	B-cell KO mice	% change	P
TV, mm3	1.28 ± 0.06	1.29 ± 0.07	0.8	≤ .685
BV, mm3	0.30 ± 0.03	0.25 ± 0.28	−16.7	≤ .003*
BV/TV, %	23.96 ± 2.76	19.87 ± 2.51	−17.1	≤ .008*
Tb. Th., μm	60.49 ± 2.78	56.21 ± 5.09	−7.1	≤ .011*
Tb. Sp., μm	222.23 ± 7.99	244.45 ± 13.66	10.0	≤ .001*
Tb. N./mm	4.54 ± 0.16	4.17 ± 0.19	−8.1	≤ .001*
SMI	0.69 ± 0.24	0.79 ± 0.21	14.5	≤ .402
Conn. D./mm3	133.48 ± 15.85	102.62 ± 18.46	−23.1	≤ .003*
Co. Th., μm	91.1 ± 3.1	82.9 ± 8.4	−9.0	≤ .002*
Co. Vol., mm3	0.47 ± 0.03	0.42 ± 0.04	−10.6	≤ .010*

Trabecular indices, including TV, BV, BV/TV, Tb. Th., Tb. Sp., Tb. N., SMI, and Conn. D., and the cortical indices Co. Th. and Co. Vol. were computed from μCT scans. The data are presented as the mean ± SD of 8 mice per group. Percentage change between WT and KO mice is indicated as “% change.” Asterisks indicate significantly different results (P ≤ .05).