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. 2007 Mar 1;35(6):1897–1907. doi: 10.1093/nar/gkm087

Figure 2.

Figure 2.

Varying patterns of RNA conservation in the NS1 and HA ORFs. (A) Consensus nucleotide and amino acid (single letter code) sequences of the first 11 codons of the overall NS1 dataset and the A and B lineages are shown along with the codon MPD scores. Residues not conserved at the 95% level are shown by asterisks. Highly conserved triplets (MPD value <0.05) are shown in red. Conserved residues that differ between lineages are highlighted. Underlining denotes the splice donor sequence. (B) Consensus sequences for the C-terminal 27 codons of HA subtypes 1, 3 and 5, encompassing the packaging signal for H1. MPD scores are not shown for clarity but conserved triplets are color-coded red (MPD < 0.05) or blue (MPD < 0.1) and highlighted. Homology between the H5 sequence and conserved nucleotides in H1 or H3 sequences are indicated by lines.