Table 3.

spr-1, but not Y74C9A.4, double stranded RNA suppresses the Egl phenotype ofsel-12(ar171) animals

Injected dsRNA	Po plates with Egl+ progeny/total (%)
Mock	0/20 (0%)
spr-1 (D1014.8)	12/14 (85%)
spr-1 (former D1014.9)	14/17 (82%)
Y74C9A.4	0/19 (0%)

sel-12(ar171) unc-1(e538) adult hermaphrodites were injected. Egl⁺, egg-laying ability was restored in their progeny. D1014.9 and D1014.8 were originally predicted to be two distinct open reading frames, but are both part of the spr-1 gene (see text and Fig. 3).