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Comparison of electrophysiological properties of WT and HD mice. Dopamine effects on voltage-gated Ca2+ current (a), GABAA current (b), and AMPA current (c) . To the right of each are summary histograms of the peak amplitudes of whole-cell currents (Left) and of the percent change induced by dopamine (DA) or the D1-class receptor agonist SKF81297 (Right) in WT (□) and HD mice (■). Data represent means ± SEM for n = 4–9; ∗, P < 0.05 compared with WT.
