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SNAP190 and OCA-B use a similar interface for communication with the Oct-1 POU domain. (A) Sequence alignment of homologous regions of SNAP190 and OCA-B. H indicates the helical region that is common to both structures. (B) Overlay of the Oct-1/U1 octamer/SNAP190 (gold), Oct-1/H2B octamer (red), and the Oct-1/H2B octamer/OCA-B (dark blue) complex structures. The SNAP190 peptide is green, and OCA-B peptide is dark gray.
