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. 2002 Apr;12(4):648–655. doi: 10.1101/gr.222902

Table 2.

Coverage of Motif Databases as a Function of Usage of IEA Protein-Function Associations

Rule seta Number of domains with a ruleb Coveragec



ProDom-NoIEA 10724 11%
CDD-NoIEA 1396 38%
 LOAD 27 49%
 Smart 353 59%
 Pfam 1016 34%
ProDom-All 17504 18%
CDD-All 1792 52%
 LOAD 31 59%
 Smart 417 75%
 Pfam 1344 47%

LOAD, Smart, and Pfam are component databases in CDD. We only considered those ProDom domains derived from at least two sequences. aDomain (sub)database and GO associations used to build rules. bTotal number of domains with at least one rule. cPercent of (sub)database for which a rule was created.