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. 2002 Apr;12(4):618–626. doi: 10.1101/gr.203402

Table 5.

Test of Pleiotropy Compared to Close Linkage

Chr 5 Chr 10 Chr 15




Likelihood ratio 5% Threshold Likelihood ratio 5% Threshold Likelihood ratio 5% Threshold






One QTL for each
 trait versus on QTL
 influencing all traits 9.38 23.24 20.81 18.53 12.72 16.72

The 5% threshold is the likelihood ratio for fitting one quantitative trait loci (QTL) explaining variation in all traits used in the analysis compared to individual QTL influencing variation in each trait separately. A ratio below the threshold implies that pleiotropy cannot be excluded at the 5% level.