Table 3.
Phylogenetic Footprinting Results for Selected Species Combinationsa
Speciesb | Number of orthologous data sets | Motif predictions with all species included | Correspondence with known sitesc |
---|---|---|---|
EC-ST | 161 | 98.8% (159/161) | 55.3% (88/159) |
EC-YP | 138 | 94.2% (130/138) | 66.9% (87/130) |
EC-VC | 112 | 83.0% (93/112) | 62.4% (58/93) |
EC-HI | 72 | 81.9% (59/72) | 62.7% (37/59) |
EC-SO | 91 | 69.2% (63/91) | 55.6% (35/63) |
EC-PA | 92 | 48.9% (45/92) | 37.8% (17/45) |
EC-BU | 27 | 85.2% (23/27) | 39.1% (9/23) |
EC-AF | 46 | 58.7% (27/46) | 48.1% (13/27) |
EC-XF | 50 | 54.0% (27/50) | 33.3% (9/27) |
EC-VC-HI | 65 | 50.8% (33/65) | 75.8% (25/33) |
EC-YP-SO | 86 | 36.0% (31/86) | 67.7% (21/31) |
EC-YP-PA | 86 | 19.8% (17/86) | 70.6% (12/17) |
EC-ST-YP-VC | 103 | 42.7% (44/103) | 86.4% (38/44) |
Results for all species combinations are in the Supplementary Data.
Species abbreviations are as follows: EC, Escherichia coli; ST, Salmonella typhi; YP, Yersinia pestis; VC, Vibrio cholerae; HI, Haemophilus influenzae; SO, Shewanella oneidensis; PA, Pseudomonas aeruginosa; BU, Buchnera sp.; AF, Acidithiobacillus ferrooxidans; and XF, Xylella fastidiosa.
Correspondence with known E. coli transcription factor binding sites was calculated only for those motif predictions that contained sites from all the species included in the data set.