Figure 1.

Scoring articles relative to gene groups. We graphically depict a small gene group of three autophagy genes (boxes with dotted boundaries). The genes are connected to their respective article references (boxes with solid boundaries). Articles about autophagy are dark boxes with white lettering. Notice that, for all genes, only a few of the referenced articles are about autophagy, the critical function that unites these genes in the group. The arrows are used to indicate the semantic neighbors of article B.2, an autophagy article. The significance of this article to the group's unifying function becomes apparent when we notice that many of its neighbors, also autophagy articles, are references for other genes in the same group.