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. 2002 Dec;12(12):1871–1884. doi: 10.1101/gr.454902

Table 3.

Consensus Sequences of Conserved Motifs in NBS Domains in Different Classes of Genes

Gene Class The P-Loop Kinase-2 RNBS-B GLPL MHD Domain






TIR-NBS-LRR GIGKTT(il)A KVL(ivl)(vi)LDDVD GSRII(iv)TT(qre)D G(gn)LPLGL MH(ndkr)LLQQ
nT-NBS-LRR GMGG(vli)GKTTL (lv)(lvi)(vl)DD(vl)W GS(kr)(vi)(lva)(fl)T(ts)R GLRLAL MHD(vm)(vlim)R(ed)
nT-NBS VGK(skr)TLV L(vi)(vi)(vi)E(lf)xxD GSK(iv)l(iv)xSR GSF(ilm)xAN Not conserved
TIR-NBS SGIGKTEL L(lv)(iv)IDNL HV(il)(iv)TTR GLW(iv)V Not conserved
*

Letters in parentheses designate residues that occur in similar frequencies at a single position. Consensus sequences of TIR and Non-TIR genes were calculated from Arabidopsis sequences (http://niblrrs.ucdavis.edu/At_RGenes). The non-LRR consensus sequences were calculated from 47 rice sequences and the TIR-NBS sequences were calculated from three rice genes and two related Arabidopsis genes.