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. 2002 Dec;12(12):1805–1814. doi: 10.1101/gr.631202

Table 3.

Molecular Function of Candidate Selection Genes

Gene ontogeny term High FST Low FST



Total number terms 183  31 
Apoptosis regulator 1 (0.5%) 0 (0.0%)
Cell adhesion molecule 4 (2.2%) 0 (0.0%)
Cell growth and/or maintenance 2 (1.1%) 0 (0.0%)
Chaperone 2 (1.1%) 0 (0.0%)
Defense/immunity protein 3 (1.6%) 2 (6.5%)
Enzyme 50 (27.3%) 5 (16.1%)
 Hydrolase 11 (6.0%) 3 (9.7%)
 Kinase 11 (6.0%) 0 (0.0%)
 Transferase 12 (6.6%) 1 (3.2%)
Enzyme regulator 4 (2.2%) 0 (0.0%)
Ligand binding or carrier 57 (31.1%) 9 (29.0%)
 Calcium binding 7 (3.8%) 0 (0.0%)
 Nucleic acid binding 23 (12.6%) 1 (3.2%)
 Protein binding 3 (1.6%) 6 (19.4%)
Motor 0 (0.0%) 1 (3.2%)
Signal transducer 27 (14.8%) 10 (32.3%)
 Ligand 4 (2.2%) 1 (3.2%)
 Receptor 14 (7.7%) 7 (22.6%)
Structural molecule 6 (3.3%) 2 (6.5%)
Transcriptional regulator 9 (4.9%) 1 (3.2%)
Transporter 18 (9.8%) 1 (3.2%)

In the Gene Oncology (GO) classification system, a parent term can have multiple subcategories, or children terms (indented text). For instance, hydrolase, kinase, and transferase are the children of the parent term enzyme. A single gene can have multiple parent and children terms (see Ashburner et al. 2000 for more specific information). Note that percentages sum to 100% for parent terms only.