Table 3.
Molecular Function of Candidate Selection Genes
Gene ontogeny term | High FST | Low FST |
---|---|---|
Total number terms | 183 | 31 |
Apoptosis regulator | 1 (0.5%) | 0 (0.0%) |
Cell adhesion molecule | 4 (2.2%) | 0 (0.0%) |
Cell growth and/or maintenance | 2 (1.1%) | 0 (0.0%) |
Chaperone | 2 (1.1%) | 0 (0.0%) |
Defense/immunity protein | 3 (1.6%) | 2 (6.5%) |
Enzyme | 50 (27.3%) | 5 (16.1%) |
Hydrolase | 11 (6.0%) | 3 (9.7%) |
Kinase | 11 (6.0%) | 0 (0.0%) |
Transferase | 12 (6.6%) | 1 (3.2%) |
Enzyme regulator | 4 (2.2%) | 0 (0.0%) |
Ligand binding or carrier | 57 (31.1%) | 9 (29.0%) |
Calcium binding | 7 (3.8%) | 0 (0.0%) |
Nucleic acid binding | 23 (12.6%) | 1 (3.2%) |
Protein binding | 3 (1.6%) | 6 (19.4%) |
Motor | 0 (0.0%) | 1 (3.2%) |
Signal transducer | 27 (14.8%) | 10 (32.3%) |
Ligand | 4 (2.2%) | 1 (3.2%) |
Receptor | 14 (7.7%) | 7 (22.6%) |
Structural molecule | 6 (3.3%) | 2 (6.5%) |
Transcriptional regulator | 9 (4.9%) | 1 (3.2%) |
Transporter | 18 (9.8%) | 1 (3.2%) |
In the Gene Oncology (GO) classification system, a parent term can have multiple subcategories, or children terms (indented text). For instance, hydrolase, kinase, and transferase are the children of the parent term enzyme. A single gene can have multiple parent and children terms (see Ashburner et al. 2000 for more specific information). Note that percentages sum to 100% for parent terms only.