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. 2002 Dec;12(12):1827–1836. doi: 10.1101/gr.606402

Table 1.

Comparison of Frequencies of Synonymous and Nonsynonymous Changes at Different Exonic Locations

Synonymous changes Nonsynonymous changes



Spliced genes
5′ end
 pos. 1–125 2596 2632
 pos. 126–250 384 460
3′ end
 pos. 1–125 2525 2370
 pos. 126–250 242 242
Single-exon genes
5′ and 3′ ends
 pos. 1–250 68 105