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. 2007 May 3;8(1):35. doi: 10.1186/1465-9921-8-35

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Copyright © 2007 Roumestan et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of desipramine and fluoxetine on leukocyte sub-populations in bronchoalveolar lavages of sensitized rats. Ovalbumin-sensitized rats (OVA) treated with saline, prednisolone (Pred, 10 mg/kg), desipramine (DMI, 10 mg/kg) or fluoxetine (Fluo, 10 mg/kg) and control rats (Cont) (n = 6–7 per group) were challenged with metacholine. Cells in bronchoalveolar lavages were spun down on cytoslides, fixated and stained. Macrophages (panel A), lymphocytes (panel B), neutrophils (panel C) and eosinophils (panel D) were then counted under a microscope. A minimum of 200 cells was counted for each bronchoalveolar lavage. *p < 0.05 and **p < 0.001 versus ovalbumin-sensitized rats treated with saline, by Student t test.