Table 2.
AM medication, non-AM adjunctive therapies, health service use, and sick leave days
| Item | Pre-study year | 0–12 months | 12–24 months | ||||
| Mean (SD) | Mean (SD) | Median difference (95%-CI) from pre-study year | P value | Mean (SD) | Median difference (95%-CI) from pre-study year | P value | |
| AM medicines per day | 0.29 (0.68) | 0.78 80.92) | 0.47 (0.36 to 0.59) | p < 0.001 | 0.47 (0.85) | 0.17 (0.09 to 0.26) | p < 0.001 |
| Non-AM medicines per day | 0.69 (1.10) | 0.82 (1.01) | 0.12 (0.04 to 0.22) | p = 0.005 | 0.68 (0.90) | 0.04 (-0.05 to 0.15) | p = 0.447 |
| Physician and dentist visits | 15.23 (15.27) | 16.64 (13.53) | 1.69 (0.19 to 2.99) | p = 0.006 | 14.84 (14.35) | -0.78 (-2.43 to 1.00) | p = 0.698 |
| Paraclinical investigations | 5.16 (5.91) | 5.85 (7.52) | 0.00 (-0.50 to 1.00) | p = 0.665 | 4.34 (5.32) | -0.98 (-1.50 to -0.08) | p = 0.011 |
| Hospital days | 4.68 (16.25) | 1.77 (5.82) | -2.50 (-8.00 to 1.00) | p = 0.123 | 3.04 (19.92) | -2.50 (-5.50 to 0.00) | p = 0.046 |
| Rehabilitation days | 0.89 (5.05) | 1.74 (6.75) | 7.00 (0.00 to 14.48) | p = 0.041 | 0.67 (3.43) | -0.62 (-0.90 to -0.56) | p = 0.008 |
| Surgeries | 0.21 (0.51) | 0.17 (0.49) | 0.00 (-0.50 to 0.00) | p = 0.342 | 0.14 (0.40) | -0.34 (-0.46 to 0.07) | p = 0.494 |
| Physiotherapy and ergotherapy sessions | 9.25 (25.98) | 11.28 (34.02) | 1.50 (-2.50 to 6.00) | p = 0.541 | 9.88 (25.95) | 0.22 (-3.59 to 5.10) | p = 0.885 |
| Psychotherapy sessions | 2.50 (8.04) | 3.12 (9.06) | 3.50 (0.50 to 7.42) | p = 0.023 | 3.58 (9.88) | 2.78 (1.72 to 6.52) | p = 0.007 |
| Sick leave days* | 22.42 (44.79) | 27.61 (71.91) | 1.24 (-7.50 to 9.00) | p = 0.748 | 26.39 (62.96) | 0.50 (-7.00 to 8.18) | p = 0.823 |
| Patients with Heilpraktiker visit (n + %)** | 21/143 (14.7%) | 18/143 (12.6%) | p = 0.571 | 22/143 (15.4%) | p = 1.000 | ||
Patients enrolled after 1 Jan 1999 with at least 3 of 5 follow-ups (n = 182). *Patients engaged in economic activity (n = 80). **Patients with complete data for all time periods.