Skip to main content
. Author manuscript; available in PMC: 2007 May 23.
Published in final edited form as: Biochemistry. 2004 Oct 26;43(42):13452–13458. doi: 10.1021/bi048892t

FIGURE 5.

FIGURE 5

Effect of Gq1 on the inhibition of telomerase activity studied by a modified TRAPEZE assay. Telomerase/Gq1 reactions were treated to remove all proteins prior to PCR detection of telomerase extension products. Lanes 1-6, the activity of telomerase in the presence of Gq1 concentrations ranging from 0 to 375 nM; lane 7, control where the telomerase extract is heat-inactivated (90 °C for 10 min); lanes 8 and 9, PCR amplification of TSR8 (not treated with telomerase extract) in the presence or absence of a large excess of Gq1 (2.5 mM); lane 10, internal PCR control experiment.