Table 2. Comparison of primary and tertiary structures of Cbl-transporters.

The upper diagonal gives sequence identities (relative to the longer sequence in each pair) and, in parenthesis, sequence similarity (‘positives’ in the substitution matrix of Henikoff and Henikoff [36]). The lower diagonal reports rms deviations of Cα-atoms for equivalenced residues in the models superimposed with DALI [22]. The number of these residues is given in parenthesis.

	Human IF	Human HC	Human TC	Bovine TC
Human IF	–	30% (48%)	23% (38%)	22% (38%)
Human HC	1.3 Å (387)	–	27% (45%)	25% (43%)
Human TC	1.6 Å (379)	1.5 Å (389)	–	73% (81%)
Bovine TC	1.2 Å (381)	1.1 Å (395)	1.2 Å (409)	–