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Induction therapy of AML reciprocally regulates Flt3 and Hdm2 proteins in vivo. AML cells sampled from a patient undergoing induction chemotherapy with an anthracycline and cytarabin were subjected to Western blotting and analyzed for Flt3, Hdm2 and p53 expression. The mean intensity on one representative Western blot was calculated and normalized to Actin. The numbers shown are in arbitrary units.
